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Wang, Aijun

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Aijun Wang
Title:
Associate Professor
Associate Investigator
Co-Director, Surgical Bioengineering Laboratory Dept. Of Surgery
University of California, Davis
Office Address: 4625 2nd Ave., Research II, Room 3005
Sacramento, CA 95817
Office Phone:
(916) 703-0422
E-Mail Address: aawang (at) ucdavis.edu
Education: Department of Surgery, University of California, Davis
Department of Biomedical Engineering, University of California, Davis
Ph.D. Biomaterials and Tissue engineering, Tsinghua University, Beijing, China
Post-Doc, Bioengineering, University of California Berkeley
Post-Doc, Stem cell engineering, Berkeley Stem Cell Center, California Institute for Regenerative Medicine (CIRM)
Research Papers: Click Here for Research Paper Links

Research Interests:

Stem cell engineering, biomaterial engineering, tissue engineering, fetal tissue engineering, fetal treatment of birth defects, vascular and neural tissue regeneration, wound healing

Current Research:

Dr. Wang’s research focuses on developing novel technologies that combine stem cell engineering and biomaterial engineering to promote tissue regeneration. The Wang Group focuses on the engineering and development of stem cells, stem cell-derived exosomes and biomaterial-based scaffolds for the treatment of a variety of surgical diseases. Projects include engineering stem cells and stem cell-derived exosomes for improved therapeutic functions and targeted delivery; engineering biomaterial scaffolds by using instructive ligands for stem cell culture, delivery and recruitment; evaluating stem cell and biomaterial products in experimental animal models and naturally occurring disease models.


Noteworthy Publications:

TITLE
AUTHOR(s)
YEAR
DOWNLOAD
Matrix Stiffness Modulates the Differentiation of Neural Crest Stem Cells In Vitro and In Vivo. Journal of Cellular Physiology. 2018. Yiqian Zhu, Xian Li, Randall Raphael R. Janairo, George Kwong, Anchi D. Tsou, Julia S. Chu, Aijun Wang, Song Li. 2018


Mesenchymal Stem Cell-Derived Exosomes: Potential Approaches to Improve Efficacy and Yield for Cell-Free Therapy. Journal of Extracellular Vesicles. 2018, 7:1, 1522236. DOI: https://doi.org/10.1080/20013078.2018.1522236 Jennifer Phan, Priyadarsini Kumar, Dake Hao, Kewa Gao, Diana Farmer, Aijun Wang. 2018
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The stem cell factor Sox2 is a positive timer of oligodendrocyte development in the postnatal murine spinal cord. Molecular Neurobiology. 2018. Accepted. Sheng Zhang, Abeer Rasai, Yan Wang, Jie Xu, Peter Bannerman, Daffcar Erol, Danayit Tsegaye, Aijun Wang, Athena Soulika, Xiangjiang Zhan, Fuzheng Guo. 2018
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In Utero Transplantation of Placenta-derived Mesenchymal Stromal Cells for Potential Application in Hemophilia A Therapy. Cell Transplantation. 2018 Jan;27(1):130-139. PMID: 29562772. DOI: 10.1177/0963689717728937 Priyadarsini Kumar, Kewa Gao, Chuwang Wang, Christopher Pivetti, Lee Lankford, Diana Farmer, Aijun Wang. 2018
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Human amnion extracellular matrix derived bioactive hydrogel for cell delivery and tissue engineering. Materials Science & Engineering C. 2018 Apr 1;85:191-202. PMID: 29407148. DOI: 10.1016/j.msec.2017.12.026 Volodymyr Ryzhuk, Xu-xin Zeng, Xijun Wang, Veniamin Melnychuk, Lee Lankford, Diana Farmer, Aijun Wang. 2018
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Differentially expressed circRNAs in melanocytes and melanoma cells and their effect on cell proliferation and invasion. Oncology Reports. 2018 Apr;39(4):1813-1824. PMID: 29436673. DOI: 10.3892/or.2018.6263 Qi Wang, Jia Chen, Aijun Wang, Lichun Sun, Li Qian, Xiao Zhou, Yu Liu, Shijie Tang, Xiang Chen, Yan Cheng, Ke Cao, Jianda Zhou. 2018
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Sox2 is Essential for Oligodendroglial Proliferation and Differentiation During Postnatal Brain Myelination and CNS Remyelination. The Journal of Neuroscience. 2018 Feb 14;38(7):1802-1820. PMID: 29335358. PMCID: PMC5815459. DOI: 10.1523/JNEUROSCI.1291-17.2018 Sheng Zhang, Xiaoqing Zhu, Xuehong Gui, Christopher Croteau, Lanying Song, Jie Xu, Aijun Wang, Peter Bannermann, Fuzheng Guo. 2018
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Stem Cells in Vascular Remodeling. Theranostics. 2018; 8(3):815-829. PMID: 29344309. PMCID: PMC5771096. DOI: 10.7150/thno.19577 Dong Wang, LeeAnn K. Li, Tiffany Dai, Aijun Wang, Song Li. 2018
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Isolation and Characterization of Canine Placenta-derived Mesenchymal Stromal Cells for the Treatment of Neurological Disorders in Dogs. Cytometry Part A. 2018; 93(1):82-92. PMID: 28715613. DOI: 10.1002/cyto.a.23171 Connor Long, Lee Lankford, Priyadarsini Kumar, Robert Grahn, Dori L. Borjesson, Diana Farmer, Aijun Wang. 2018
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Fetal Surgical Repair with Placenta-derived Mesenchymal Stromal Cell Engineered Patch in a Rodent Model of Myelomeningocele. The Journal of Pediatric Surgery. 2018, 53:183-188. DOI: https://doi.org/10.1016/j.jpedsurg.2017.10.040 Y. Julia Chen, Karen Chung, Christopher Pivetti, Lee Lankford, Sandra Kabagambe, Melissa Vanover, James Becker, Chelsey Lee, Josephine Tsang, Aijun Wang, Diana Farmer. 2018
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Placental Mesenchymal Stromal Cells Seeded on Clinical Grade Extracellular Matrix Improve Ambulation in Ovine Myelomeningocele. The Journal of Pediatric Surgery. 2018, 53:178-182. DOI: https://doi.org/10.1016/j.jpedsurg.2017.10.032 Sandra Kabagambe, Benjamin Keller, James Becker, Laura Goodman, Christopher Pivetti, Lee Lankford, Karen Chung, Chelsey Lee, Y. Julia Chen, Priyadarsini Kumar, Melissa Vanover, Aijun Wang, Diana Farmer. 2018
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Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery. eLife. 2017; 6:e31101. PMID:29271742. PMCID: PMC5768420. DOI: 10.7554/eLife.31101 Ting-Ya Chang, Chen Chen, Ya-Chu Chang, Chi-Huan Lu, Min Lee, Shao-Tzu Lu, De-Yao Wang, Aijun Wang, Chin-Lin Guo, Pei-Lin Cheng. 2017
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The Differentiation Stage of Transplanted Stem Cells Modulates Nerve Regeneration. Scientific Reports. 2017; 7(1):17401. PMID: 29234013. PMCID: PMC5727226. DOI: 10.1038/s41598-017-17043-4 Ching-Wen Huang, Wen-Chin Huang, Xuefeng Qiu, Flavia Fernandes Ferreira da Silva, Aijun Wang, Shyam Patel, Leon J. Nesti, Mu-Ming Poo, Song Li. 2017
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Isolation of a Myogenic Progenitor Cell Population from Human Placenta: a pilot study. The Journal of Pediatric Surgery. 2017; 52(12):2078-2082. PMID: 28964407. DOI: 10.1016/j.jpedsurg.2017.08.025 Sandra Kabagambe, Lee Lankford, Priyadarsini Kumar, Y. Julia Chen, Kyle Herout, Chelsey Lee, Rebecca Stark, Diana Farmer, Aijun Wang. 2017
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Potential clinical applications of placental stem cells for use in fetal therapy of birth defects. Placenta. 2017, 59:107-112. PMID: 28651900. DOI: 10.1016/j.placenta.2017.05.010 Melissa Vanover, Aijun Wang, Diana Farmer. 2017
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microRNA-33a-5p increases radiosensitivity by modulating glycolysis in melanoma cells. Oncotarget. 2017; 8:83660-83672. DOI: 10.18632/oncotarget.19014 Ke Cao, Jingjing Li, Jia Chen, Li Qian, Aijun Wang, Xiang Chen, Wei Xiong, jingtian tang, Shijie Tang, Yong Chen, Yao Chen, Yan Cheng, Jianda Zhou. 2017
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Sox10+ cells contribute to vascular development in multiple organs. Arteriosclerosis, Thrombosis, and Vascular Biology. 2017 Sep;37(9):1727-1731. PMID: 28751573 PMCID: PMC5572822. DOI: https://doi.org/10.1161/ATVBAHA.117.309774 Dong Wang, Fan Wu, Haoyong Yuan, Aijun Wang, Gyeong Jin Kang, Tan Truong, Lu Chen, Andrew S. McCallion, Xiaohua Gong, Song Li. 2017
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Viability and Biomechanics of Diced Cartilage Blended with Platelet-Rich Plasma and Wrapped with Poly (Lactic-Co-Glycolic) Acid Membrane. The Journal of Craniofacial Surgery. 2017; 28(6):1418-1424. PMID: 28692513. DOI: 10.1097/SCS.0000000000003739 Junlin Liao, Jia Chen, Bin He, Yong Chen, Jiaqun Xu, Hongju Xie, Feng Hu, Aijun Wang, Chengqun Luo, Qingfeng Li, Jianda Zhou. 2017
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Effect of 2-octylcyanoacrylate on placenta derived mesenchymal stromal cells on extracellular matrix. Placenta. 2017 Apr 2. pii: S0143-4004(17)30222-9. PMID: 28465002. DOI: 10.1016/j.placenta.2017.03.022 Y. Julia Chen, Lee Lankford, Sandra Kabagambe, Zoe Saenz, Priyadarsini Kumar, Diana Farmer, Aijun Wang. 2017
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Engineering the mechanical and biological properties of nanofibrous vascular grafts for in situ vascular tissue engineering. Biofabrication. 2017; 9(3):035007. PMID: 28817384. PMCID: PMC5847368. DOI: 10.1088/1758-5090/aa834b Jeffrey Henry, Jian Yu, Aijun Wang, Randall Lee, Jun Fang, Song Li. 2017
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Manufacture and preparation of human placenta-derived mesenchymal stromal cells for local tissue delivery. Cytotherapy. 2017 Jun; 19(6):680-688. PMID: 28438482. DOI: 10.1016/j.jcyt.2017.03.003 Lee Lankford, Y. Julia Chen, Zoe Saenz, Priyadarsini Kumar, Connor Long, Diana Farmer, Aijun Wang. 2017
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Discovery and characterization of a potent and specific peptide ligand targeting endothelial progenitor cells and endothelial cells for tissue regeneration. ACS Chem. Biol. 2017, 12 (4), 1075–1086. PMID: 28195700. DOI: 10.1021/acschembio.7b00118 Dake Hao, Wenwu Xiao, Ruiwu Liu, Priyadarsini Kumar, Yuanpei Li, Ping Zhou, Fuzheng Guo, Diana L Farmer, Kit S. Lam, Fengshan Wang, Aijun Wang. 2017
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Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways. Stem Cells. 2017. In press. DOI: 10.1002/stem.2577 Aja Harding, Elizabeth Cortez-Toledo, Nataly Magner, Julie Beegle, Dane Coleal-Bergum, Dake Hao, Aijun Wang, Jan Nolta, Ping Zhou. 2017
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Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. Scientific Reports. 2017 Jan 10;7:40295. PMCID: PMC5223127. DOI: 10.1038/srep40295 Dong Wang/Aijun Wang (Co-first author), Fan Wu, Xuefeng Qiu, Ye Li, Julia Chu, WC Huang, Kang Xu, Xiaohua Gong, Song Li. 2017
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Age Does Matter: A Pilot Comparison of Placenta-Derived Stromal Cells for in Utero Repair of Myelomeningocele Using a Lamb Model. Fetal Diagnosis and Therapy. 2016;39(3):179-85. PMID: 26159889 DOI: 10.1159/000433427 Erin G. Brown, Benjamin A. Keller, Lee Lankford, Christopher D. Pivetti, Shin Hirose, Diana L. Farmer, Aijun Wang. 2016
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Editorial: Neurorestoratologic Strategies and Mechanisms in the Nervous System. BioMed Research International. 2015:163170. PMID: 26491655. PMCID: PMC4603317 DOI: 10.1155/2015/163170 Lin Chen, Qiang Ao, Hari Shanker Sharma, Aijun Wang, Shiqing Feng. 2015
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The beneficial effects of the herbal medicine Di-huang-yin-zi (DHYZ) on patients with ischemic stroke: A randomized, placebo controlled clinical study. Complementary Therapies in Medicine, 2015; 23(4): 591–597. PMID: 26275652. DOI: 10.1016/j.ctim.2015.06.003 Mei Yu, Zhi-Jun Sun, Lian-Tao Li, Hong-You Ge, Chang-Qin Song, Aijun Wang. 2015
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Placental Mesenchymal Stromal Cells Rescue Ambulation in Ovine Myelomeningocele. Stem Cells Translational Medicine. 2015 Jun; 4(6):659-69. #Corresponding author. PMID: 25911465 PMCID: PMC4449103 DOI: 10.5966/sctm.2014-0296 Aijun Wang, Erin G. Brown, Benjamin A. Keller, Christopher D. Pivetti, Nicole A. Sitkin, Michael S. Beattie, Jacqueline C. Bresnahan, Diana L. Farmer. 2015
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Development of a Locomotor Rating Scale for Testing Motor Function in Sheep. The Journal of Pediatric Surgery. 2015 Apr;50(4):617-21. PMID: 25840074. DOI: 10.1016/j.jpedsurg.2015.01.002 Erin G. Brown, Benjamin A. Keller, Christopher D. Pivetti, Nicole A. Sitkin, Aijun Wang, Diana L. Farmer, Jacqueline C. Bresnahan. 2015
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Placenta as a Source of Stem Cells for Regenerative Medicine. Current Pathobiology Reports. 2015, March; 3(1): 9-16. DOI: 10.1007/s40139-015-0070-6 Jason A. Meierhenry, Volodymyr Ryzhuk, Maricel G. Miguelino, Lee Lankford, Jerry S. Powell, Diana Farmer, Aijun Wang. 2015
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Early Gestation Chorionic Villi-derived Stromal Cells for Fetal Tissue Engineering. World Journal of Stem Cells. 2015 Jan; 7(1): 195-207. PMCID: PMC4300931 DOI: 10.4252/wjsc.v7.i1.195 Lee Lankford, Taryn Selby, James Becker, Volodymyr Ryzhuk, Connor Long, Diana Farmer, Aijun Wang. 2015
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A novel Bruch's membrane-mimetic electrospun substrate scaffold for human retinal pigment epithelium cells. Biomaterials 2014 Dec;35(37):9777-88. PMID: 25220295. DOI: 10.1016/j.biomaterials.2014.08.040 Ping Xiang, Kun-Chao Wu, Ying Zhu, Lue Xiang, Chong Li, Deng-Long Chen, Feng Chen, Guotong Xu, Aijun Wang, Min Li, Zi-Bing Jin. 2014
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Lentiviral vectors enveloped with rabies virus glycoprotein can be used as a novel retrograde tracer to assess nerve recovery in rat sciatic nerve injury models. Cell and Tissue Research. 2014 Feb; 355(2):255-66. PMID: 24326614. DOI: 10.1007/s00441-013-1756-x Yujun Wei, Kai Gong, Qiang Ao, Aijun Wang, Yandao Gong, Huancong Zuo, Yuqi Zhang, James Wang, Guihuai Wang. 2014
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In utero repair of myelomeningocele with autologous amniotic membrane in the fetal lamb model. The Journal of Pediatric Surgery. 2014 Jan; 49(1):133-7; discussion 137-8. PMID: 24439597. DOI: 10.1016/j.jpedsurg.2013.09.043 Erin Brown, Payam Saadai, Christopher Pivetti, Michael Beattie, Jacqueline Bresnahan, Aijun Wang, Diana Farmer. 2014
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Human iPSC-derived Neural Crest Stem Cells Promote Tendon Repair in a Rat Patellar Tendon Window Defect Model. Tissue Eng Part A. 2013 Jul; 19(21-22): 2439-2451. PMID: 23815150. PMCID: PMC3807699. DOI: 10.1089/ten.TEA.2012.0453 Wei Xu, Yequan Wang, Erfu Liu, Yanjun Sun, Ziwei Luo, Zhiling Xu, Wanqian Liu, Li Zhong, Yonggang Lv, Aijun Wang, Zhenyu Tang, Song Li, Li Yang. 2013
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Synovial stem cells and their responses to the porosity of microfibrous scaffold. Acta Biomaterialia. 2013 Jul; 9(7):7264-75. PMID: 23523935. PMCID: PMC3669641. DOI: 10.1016/j.actbio.2013.03.009 Benjamin Lee, Zhenyu Tang, Aijun Wang, Fang Huang, Zhiqiang Yan, Dong Wang, Julia Chu, Li Yang, Song Li. 2013
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Vascular Smooth Muscle Cells: To Be or Not To Be? Circulation Research. 2013 Jan;112(1):23-6. PMID: 23093574. DOI: 10.1161/CIRCRESAHA.112.281055 Zhenyu Tang, Aijun Wang, Dong Wang, Song Li. 2013
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Human Induced Pluripotent Stem Cell-derived Neural Crest Stem Cells Integrate into the Injured Spinal Cord in the Fetal Lamb Model of Myelomeningocele. The Journal of Pediatric Surgery. 2013 Jan; 48(1):158-63. #Corresponding author. PMID: 23331809. DOI: 10.1016/j.jpedsurg.2012.10.034 Payam Saadai, Aijun Wang#, Yvette Nout, Timothy Downing, Michael Beattie, Jacqueline Bresnahan, Song Li, Diana Farmer. 2012
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The effect of stromal cell-derived factor-1α/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. Biomaterials. 2012 Nov; 33(32):8062-74. PMID: 22884813. PMCID: PMC3488434. DOI: 10.1016/j.biomaterials.2012.07.042 Jian Yu/Aijun Wang (Co-first author), Zhenyu Tang, Yiqian Zhu, Jeffrey Henry, Fengping Huang, Song Li. 2012
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Differentiation of Multipotent Vascular Stem Cells Contributes to Vascular Diseases. Nature Communications. 2012 Jun 6; 3:875. PMID: 22673902. PMCID: PMC3538044. DOI: 10.1038/ncomms1867. Reported by over 100 major news outlets worldwide: NPR’s Science Friday, SF Chronicle (FRONT page on 6/6/2012), Fox News, Medical News Today, US News & World Report, Daily Mail (UK), etc. The study was highlighted in Nature, 486, 9 (07 June 2012) DOI:10.1038/486009d. Zhenyu Tang/Aijun Wang (Co-first author), Zhiqiang Yan, Bo Liu, Julia Chu, Jill Helms, Song Li. 2012
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Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair. Journal of Controlled Release. 2012 May 23; 161(3):910-917. PMCID: PMC3698241. DOI: 10.1016/j.jconrel.2012.05.034 Timothy Downing/Aijun Wang (Co-first author), Zhiqiang Yan, Yvette Nout, Andy Lee, Michael S. Beattie, Jacqueline C. Bresnahan, Diana L. Farmer, Song Li. 2012
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Femtosecond Laser Ablation Enhances Cell Infiltration into Three-Dimensional Electrospun Scaffolds. Acta Biomaterialia. 2012 Jul;8(7):2648-58. PMID: 22522128. PMCID: PMC3425609. DOI: 10.1016/j.actbio.2012.04.023 Benjamin Lee, Hojeong Jeon, Aijun Wang, Zhiqiang Yan, Jian Yu, Costas Grigoropoulos, Song Li. 2012
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Derivation of Smooth Muscle Cells with Neural Crest Origin from Human Induced Pluripotent Stem Cells. Cells Tissues Organs. 2012;195:5-14. PMID: 22005509. PMCID: PMC3257812. DOI: 10.1159/000331412 Aijun Wang, Zhenyu Tang, Xian Li, Yisu Jiang, Danielle A. Tsou, Song Li. 2012
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Effects of Fluid Shear Stress on a Distinct Population of Vascular Smooth Muscle Cells. Cell and Molecular Bioengineering. 2011;4:627-36. PMID: 22924082. PMCID: PMC3425612. DOI: 10.1007/s12195-011-0205-8 Steven Hsu, Julia Chu, Fanqing F. Chen, Aijun Wang, Song Li. 2011
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Prenatal Repair of Myelomeningocele with Aligned Nanofibrous Scaffolds - A Pilot Study in Sheep. The Journal of Pediatric Surgery. 2011,46:2279-83. PMID: 22152865. DOI: 10.1016/j.jpedsurg.2011.09.014 Payam Saadai, Yvette Nout, Jose Encinas, Aijun Wang, Timothy Downing, Michael S. Beattie, Jacqueline C. Bresnahan, Song Li, Diana L. Farmer. 2011
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Uniaxial Mechanical Strain Modulates the Differentiation of Neural Crest Stem Cells into Smooth Muscle Lineage on Micropatterned Surfaces. PLoS ONE. 2011, 6(10): e26029. PMID: 22016804. PMCID: PMC3189240. DOI: 10.1371/journal.pone.0026029 Xian Li, Julia S. Chu, Aijun Wang, Yiqian Zhu, Wai Keung Chu, Li Yang, Song Li. 2011
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Chitosan/silk Fibroin-based Tissue-engineered Graft Seeded with Adipose-derived Stem Cells Enhances Nerve Regeneration in a Rat Model. Journal of Materials Science: Materials in Medicine. 2011, 22(8):1947-64. PMID: 21656031. DOI: 10.1007/s10856-011-4370-z Yujun Wei, Kai Gong, Zhenghuan Zheng, Aijun Wang, Qiang Ao, Yandao Gong, Xiufang Zhang. 2011
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Induced Pluripotent Stem Cells for Neural Tissue Engineering. Biomaterials. 2011, 32(22):5023-32. PMID: 21514663. PMCID: PMC3100451. DOI: 10.1016/j.biomaterials.2011.03.070 Aijun Wang, Zhenyu Tang, In-Hyun Park, Yiqian Zhu, Shyam Patel, George Q. Daley, Song Li. 2011
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The Effect of Matrix Stiffness on the Differentiation of Mesenchymal Stem Cells in Response to TGF-β. Biomaterials. 2011, 32(16):3921-30. PMID: 21397942. PMCID: PMC3073995. DOI: 10.1016/j.biomaterials.2011.02.019 Jennifer S. Park, Anchi D. Tsou, Rokhaya Diop, Zhenyu Tang, Aijun Wang, Song Li. 2011
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Engineering Bi-layer Nanofibrous Conduits for Peripheral Nerve Regeneration. Tissue Engineering. 2011, 17(7):705-15. PMID: 21501089. PMCID: PMC3124110. DOI: 10.1089/ten.tec.2010.0565 Yiqian Zhu/Aijun Wang (Co-first author), Shyam Patel, Kyle Kurpinski, Edward Diao, Xuan Bao, George Kwong, William L. Young, Song Li. 2011
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Regulation of Neural Differentiation and Axon Growth by Growth Factors and Bioactive Nanofibers. Tissue Engineering. 2010, 16(8):2641-8. PMID: 20367289. PMCID: PMC2947452. DOI: 10.1089/ten.TEA.2009.0414 Hayley Lam, Shyam Patel, Aijun Wang, Julia Chu, Song Li. 2010
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Schwann-like Cells Differentiation of Rat Adipose-derived Stem Cells by Indirect Co-culture with Schwann Cells in vitro. Cell Proliferation. 2010, 43(6):606-16. PMID: 21039999. DOI: 10.1111/j.1365-2184.2010.00710.x Yujun Wei, Zhenghuan Zheng, Lingling Liu, Aijun Wang, Lihai Zhang, Qiang Ao, Yandao Gong, Xiufang Zhang. 2010
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The Effect of Topology of Chitosan Biomaterials on the Differentiation and Proliferation of Neural Stem Cells. Acta Biomaterialia. 2010, 6(9), 3630-9. PMID: 20371303. DOI: 10.1016/j.actbio.2010.03.039 Gan Wang, Qiang Ao, Kai Gong, Aijun Wang, Yandao Gong, Xiufang Zhang. 2010
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Nanofibrous Patches for Spinal Cord Regeneration. Advanced Functional Materials. 2010, 20(9), 1433-40. PMID: 23378825. PMCID: PMC3558949. DOI: 10.1002/adfm.200901889 Yiqian Zhu/Aijun Wang (Co-first author), Wenqian Shen, Shyam Patel, Rong Zhang, William Young, Song Li. 2010
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TGF-b and Notch Signaling Mediate Stem Cell Differentiation into Smooth Muscle Cells. Stem Cells. 2010, 28(4), 734-42. PMID: 20146266. DOI: 10.1002/stem.319 Kyle Kurpinski, Hayley Lam, Julia Chu, Aijun Wang, Ahra Kim, Eric Tsay, Smita Agrawal, David Schaffer, Song Li. 2010
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The Behavior of MC3T3-E1 Cells on Chitosan/poly-L-lysine Composite Films: Effect of Nanotopography, Surface Chemistry, and Wettability. Journal of Biomedical Materials Research Part A. 2009, 89A(2):453-65. PMID: 18431777. DOI: 10.1002/jbm.a.31979 Zhenhuan Zheng, Ling Zhang, Lijun Kong, Aijun Wang, Yandao Gong, Xiufang Zhang. 2009
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An Improved Method for Isolating Schwann Cells from Postnatal Rat Sciatic Nerves. Cell and Tissue Research. 2009, 337(3):361-9. PMID: 19639342. DOI: 10.1007/s00441-009-0836-4 Yujun Wei, Jianli Zhou, Zhenghuan Zheng, Aijun Wang, Qiang Ao, Yandao Gong, Xiufang Zhang. 2009
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Surface Properties of Chitosan Films Modified with Polycations and Their Effects on the Behavior of PC12 Cells. Journal of Bioactive and Compatible Polymers. 2009, 24(1): 63-82. DOI: 10.1177/0883911508099653 Zhenhuan Zheng, Yujun Wei, Gan Wang, Aijun Wang, Qiang Ao, Xiufang Zhang, 2009
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LEF-1 Activates the Transcription of E2F1. Biochemical and Biophysical Research Communications. 2008, 365(1):149-53. PMID:17980157. DOI: 10.1016/j.bbrc.2007.10.138 Fangfang Zhou, Long Zhang, Kai Gong, Guangyuan Lu, Baiyang Sheng, Aijun Wang, Nanming Zhao, Xiufang Zhang, Yandao Gong. 2008
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The association of GSK3β with E2F1 Facilitates NGF-induced Neural Cell Differentiation. The Journal of Biological Chemistry 2008, 283(21):14506-15. PMID: 18367454. DOI: 10.1074/jbc.M706136200 Fangfang Zhou, Long Zhang, Aijun Wang, Bo Song, Kai Gong, Lihai Zhang, Min Hu, Xiufang Zhang, Nanming Zhao, Yandao Gong. 2008
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Preparation and Characterization of a Multilayer Biomimetic Scaffold for Bone Tissue Engineering. Journal of Biomaterials Applications. 2007, 22(3):223-39. PMID: 17255157. DOI: 10.1177/0885328206073706 Lijun Kong, Qiang Ao, Aijun Wang, Kai Gong, Xi Wang, Guangyuan Lu, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2007
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Combined Transplantation of Neural Stem Cells and Olfactory Ensheathing Cells for the Repair of Spinal Cord Injuries. Medical Hypotheses. 2007, 69(6):1234-7. PMID: 17548168. DOI: 10.1016/j.mehy.2007.04.011 Qiang Ao/Aijun Wang (Co-first author), Guoqiang Chen, Shijie Wang, Huancong Zuo, Xiufang Zhang. 2007
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Physical Properties and Biocompatibility of a Porous Chitosan-based Fibre-reinforced Conduit for Nerve Regeneration. Biotechnology Letters. 2007, 29(11):1697-702. PMID: 17628751. DOI: 10.1007/s10529-007-9460-0 Aijun Wang, Qiang Ao, Yujun Wei, Kai Gong, Nanming Zhao, Yandao Gong, Xiufang Zhang. 2007
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In Vitro Cytotoxicity and Protein Drug Release Properties of Chitosan/Heparin Microspheres. Tsinghua Science and Technology. 2007, 12(4): 361-5. DOI: 10.1016/S1007-0214(07)70054-8 http://dx.doi.org/10.1016/S1007-0214(07)70054-8 Qing He, Qiang Ao, Aijun Wang, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2007
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Effect of Multilayer Biomimetic Nano-hydroxyapatite/chitosan Composite Scaffolds on Repairing Rabbit Fibula Defect. Journal of Clinical Rehabilitative Tissue Engineering Research. 2007,11(5):815-8. (in Chinese) Lijun Kong, Qiang Ao, Aijun Wang, Kai Gong, Xi Wang, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2007


Protective Effects of Extract of Ginkgo Biloba (EGb 761) on Nerve Cells after Spinal Cord Injury in Rats. Spinal Cord. 2006, 44(11): 662-7. PMID: 16415923. DOI: 10.1038/sj.sc.3101900 Qiang Ao, Xiuhua Sun, Aijun Wang, Panfeng Fu, Kai Gong, Yandao Gong, Xiufang Zhang. 2006
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Encapsulation of Drug Reservoirs in Fibers by Emulsion Electrospinning: Morphology Characterization and Preliminary Release Assessment. Biomacromolecules. 2006, 7(8): 2327-30. PMID: 16903678. DOI: 10.1021/bm060264z Hongxu Qi, Ping Hu, Jun Xu, Aijun Wang. 2006
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A Sandwich Tubular Scaffold Derived from Chitosan for Blood Vessel Tissue Engineering. Journal of Biomedical Materials Research Part A. 2006, 77A(2):277-84. PMID: 16400655. DOI: 10.1002/jbm.a.30614 Ling Zhang, Qiang Ao, Aijun Wang, Guangyuan Lu, Lijun Kong, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2006
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Manufacture of Multi-microtubule Chitosan Nerve Conduits with Novel Molds and Characterization in vitro. Journal of Biomedical Materials Research Part A. 2006, 77A(1):11-8. PMID: 16345091. DOI: 10.1002/jbm.a.30593 Qiang Ao, Aijun Wang, Wenling Cao, Ling Zhang, Lijun Kong, Qing He, Yandao Gong, Xiufang Zhang. 2006
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Porous Chitosan Tubular Scaffolds with Knitted Outer Wall and Controllable Inner Structure for Nerve Tissue Engineering. Journal of Biomedical Materials Research Part A. 2006, 79A(1): 36-46. PMID: 16758450. DOI: 10.1002/jbm.a.30683 Aijun Wang, Qiang Ao, Wenling Cao, Mingzhi Yu, Qing He, Lijun Kong, Ling Zhang, Yandao Gong, Xiufang Zhang. 2006
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Neural Stem Cell Affinity of Chitosan and Feasibility of Chitosan-based Porous Conduits as Scaffolds for Nerve Tissue Engineering. Tsinghua Science and Technology. 2006, 11(4):415-20. http://dx.doi.org/10.1016/S1007-0214(06)70210-3 Aijun Wang, Qiang Ao, Qing He, Xiaoming Gong, Kai Gong, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2006
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Fiber-based Chitosan Tubular Scaffolds for Soft Tissue Engineering: Fabrication and in vitro Evaluation. Tsinghua Science and Technology. 2005, 10(4):449-53. DOI: 10.1016/S1007-0214(05)70099-7 http://dx.doi.org/10.1016/S1007-0214(05)70099-7 Aijun Wang, Qiang Ao, Wenling Cao, Chang Zhao, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2005
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Novel Biodegradable Films and Scaffolds of Chitosan Blended with Poly(3-hydroxybutyrate). Journal of Biomaterials Science, Polymer Edition. 2005, 16(11):1379-94. PMID: 16370239. DOI: 10.1163/156856205774472308 Wenling Cao, Aijun Wang, Duohui Jing, Yandao Gong, Nanming Zhao, and Xiufang Zhang. 2005
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Fabrication and Characterization of Chitosan Nerve Conduits with Microtubular Architecture. Tsinghua Science and Technology. 2005, 10(4):435-8. DOI: 10.1016/S1007-0214(05)70096-1 Qiang Ao, Aijun Wang, Wenling Cao, Chang Zhao, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2005
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Preparation of Porous Multi-channeled Chitosan Conduits for Nerve Tissue Engineering. Key Engineering Materials. 2005, (288-289): 27-30. DOI: 10.4028/www.scientific.net/KEM.288-289.27 Qiang. Ao, Aijun Wang, Wengling Cao, Chang Zhao, Yandao Gong, Nanming Zhao, Xiufang Zhang. 2005
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