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Isseroff, Roslyn

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Title:
Professor
Office Address: UC Davis, Dept. of Dermatology, TB 192,
Davis, CA 95616
Office Phone:
(530) 752-9767
E-Mail Address: rrisseroff (at) ucdavis.edu
Education: Brooklyn College, City University of New York, Brooklyn, NY,
1967-1971, BS Biology (w/ honors)
Albert Einstein College of Medicine, Bronx, NY,
1971-1975, MD
Research Papers: Click Here for Research Paper Links

Research Interests:

Wound healing, cell migration, tissue engineering.

Current Research:

Electrical stimulation of wound healing, understanding how skin cells respond to endogenous wound currents. Beta adrenergic receptor modulation of wound healing.


Noteworthy Publications:

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AUTHOR(s)
YEAR
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Stress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for Beta blockers. PLoS Med. 6(1):e12. Sivamani RK, Pullar CE, Manabat-Hidalgo CG, Rocke DM, Carlsen RC, Greenhalgh DG, Isseroff RR. 2009
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An Epinephrine-Dependent Mechanism for the Control of UV-Induced Pigmentation 2009
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Responses of the 27-kDa heat shock protein to UVB irradiation in human epidermal melanocytes Shi B, Grahn JC, Reilly DA, Dizon TC, Isseroff RR. 2008
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Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging. J Invest Dermatol. 128(7):1812-20. Kim MH, Liu W, Borjesson DL, Curry FR, Miller LS, Cheung AL, Liu FT, Isseroff RR, Simon SI. 2008
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Beta2-adrenergic receptor signaling mediates corneal epithelial wound repair. Invest Ophthal Vis Sci. 49(5):1857-63. Ghoghawala SY, Mannis MJ, Pullar CE, Rosenblatt MI, Isseroff RR. 2008
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Label-retaining cells of the bladder: candidate urothelial stem cells. Am J Physiol Renal Physiol. 294(6):F1415-21. Kurzrock EA, Lieu DK, deGraffenried LA, Chan CW, Isseroff RR 2008
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beta-Adrenergic receptor modulation of wound repair. Pharmacol Res. 58(2):158-64. Pullar CE, Manabat-Higalgo C, Bolaji R, Isseroff RR. 2008
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Beta-adrenergic receptor agonists delay while antagonists accelerate epithelial wound healing: evidence of an endogenous adrenergic network within the corneal epithelium. J Cell Physiol. 2007 Apr;211(1):261-72 Pullar CE, Zhao M, Song B, Pu J, Reid B, Ghoghawala S, McCaig C, Isseroff RR. 2007
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Urothelial progenitor cells: regional differences in the rat bladder. Cell Prolif. 2007 Apr;40(2):157-65. Nguyen MM, Lieu DK, deGraffenried LA, Isseroff RR, Kurzrock EA. 2007
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Wound re-epithelialization: modulating keratinocyte migration in wound healing. Front Biosci. 2007 May 1;12:2849-68. Raja, Sivamani K, Garcia MS, Isseroff RR. 2007
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Beta1 integrin expression pattern in transitional urothelium does not allow for efficient stem cell enrichment as in other epithelia. Tissue Eng. 2007 Feb;13(2):263-70. Lieu DK, Degraffenried LA, Isseroff RR, Kurzrock EA. 2007
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Beta adrenergic receptors in keratinocytes. Dermatol Clin. 2007 Oct;25(4):643-53 Sivamani RK, Lam ST, Isseroff RR. 2007
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Association between the use of beta-adrenergic receptor agents and the development of venous leg ulcers. Arch Dermatol. 2007 Oct;143(10):1275-80 Margolis DJ, Hoffstad O, Isseroff RR. 2007
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Responses of the 27-kDa heat shock protein to UVB irradiation in human epidermal melanocytes. Exp Dermatol. 2007 Nov 21; [Epub ahead of print] Shi B, Grahn JC, Reilly DA, Dizon TC, Isseroff RR. 2007
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Microneedle array for measuring wound generated electric fields. Conf Proc IEEE Eng Med Biol Soc. 2006;1:4326-8. Mukerjee EV, Isseroff RR, Nuccitelli R, Collins SD, Smith RL. 2007
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beta-Adrenergic receptor antagonists accelerate skin wound healing: evidence for a catecholamine synthesis network in the epidermis. J Biol Chem. 2006 Jul 28;281(30):21225-35. Pullar CE, Rizzo A, Isseroff RR. 2006
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beta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1. Mol Biol Cell. 2006 Nov;17(11):4925-35. Pullar CE, Baier BS, Kariya Y, Russell AJ, Horst BA, Marinkovich MP, Isseroff RR. 2006
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The beta 2-adrenergic receptor activates pro-migratory and pro-proliferative pathways in dermal fibroblasts via divergent mechanisms. J Cell Sci. Feb 1;119(Pt 3):592-602. Pullar CE, Isseroff RR. 2006
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Arsenite pre-conditioning reduces UVB-induced apoptosis in corneal epithelial cells through the anti-apoptotic activity of 27 kDa heat shock protein (HSP27). J Cell Physiol. 2006 Feb;206(2):301-8. Shi B, Isseroff RR. 2006
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Beta2-adrenergic receptor activation delays wound healing. FASEB J. Jan;20(1):76-86. Pullar CE, Grahn JC, Liu W, Isseroff RR. 2006
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